Bariatric Surgery  >  Health Benefits  >  Cancer Risks with Morbid Obesity

Morbid Obesity and Cancer Risks

Several studies have been conducted to examine the link between morbid obesity and cancer. In 2001, experts at the National Cancer Institute concluded that several cancers are associated with obesity:

  • Colon cancer
  • Breast cancer (postmenopausal)
  • Endometrial cancer (lining of the uterus)
  • Kidney cancer
  • Esophageal cancer (adenocarcinoma)

In 2003, an article in the New England Journal of Medicine estimated that obesity could account for 14% of all deaths from cancer in men and 20% of all deaths from cancer in women

A Proven Treatment Option
Several clinical studies of bariatric surgery show that surgery improved life expectancy in patients by at least 29 to 89 percent.

A Note on Relative Risk
The charts below refer to “relative risk,” which compares how likely an event is to occur to a person versus another person. The charts show how much more likely a person with morbid obesity is to develop cancer or die from cancer versus a person with a healthy weight.


National Cancer Institute Found People Living with Morbid Obesity Are More Likely to Develop Certain Cancers Than Healthy Weight People.

Table 1: National Cancer Institute Morbid Obesity Relative Risk
Type of Cancer Women Men
Esophageal Adenocarcinoma 200% higher relative risk of occurrence 200% higher relative risk of occurrence
Kidney Cancer 84% higher relative risk of occurrence 84% higher relative risk of occurrence
Colon Cancer No data available Increased risk of occurrenc
Breast cancer 50% higher relative risk of occurrence No data available
Uterine cancer 200% to 400% higher relative risk of occurrence Not Applicable


Study in the New England Journal of Medicine Found People Living with Morbid Obesity Had Significantly Higher Death Rates from Cancer Than Healthy Weight People.

Table 2: National Cancer Institute Morbid Obesity Relative Risk
Type of Cancer Women Men
All types

62% higher relative risk of death 52% higher relative risk of death
Esophageal cancer (adenocarcinoma) No data available 63% higher relative risk of death
Kidney cancer 475% higher relative risk of death 70% higher relative risk of death
Stomach cancer 8% higher relative risk of death 94% higher relative risk of death
Colorectal cancer 46% higher relative risk of death 84% higher relative risk of death
Liver cancer 68% higher relative risk of death 452% higher relative risk of death
Pancreatic cancer 276% higher relative risk of death 49% higher relative risk of death
Non-Hodgkin’s lymphoma 95% higher relative risk of death 49% higher relative risk of death
Multiple myeloma 44% higher relative risk of death 71% higher relative risk of death
Leukemia Lower relative risk of death 70% higher relative risk of death
Breast cancer 212% higher relative risk of death No data available
Cervical cancer 320% higher relative risk of death N/A
Ovarian cancer 51% higher relative risk of death> N/A
Uterine cancer 625% higher relative risk of death N/A
Prostate cancer N/A 34% higher relative risk of death


Cancer and obesity seem tol be linked, but there is hope. One recent study that examined the effect of intentional weight loss found that women who experienced intentional weight loss of 20 or more pounds and were not currently overweight had cancer rates at the level of healthy women who never lost weight. Several clinical studies found that bariatric surgery reduced mortality in patients by 29% to 89% when compared to a group of people living with morbid obesity who had not had the surgery.

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